Notwithstanding the high IVF success rate in India, there are instances where even multiple rounds of IVF do not bear fruit. However, innovations in the field of IVF have given birth to a slew of techniques that can be used to improve the chances of conception for couples who have suffered multiple IVF failure. IMSI, or Intracytoplasmic Morphologically selected Sperm Injection, is one such technique. As it is offered as part of the normal IVF protocol, its expense related to it is only marginally higher than the IVF treatment cost in India.
A fertility clinic in India that offers ICSI, Intra-Cytoplasmic Sperm Injection, usually also offers IMSI as the latter is a technique that builds upon the benefits of the former. So while an egg is injected with a sperm in ICSI, IMSI refines that process further by carefully selecting the best sperm before injecting it into an egg.
IMSI is made possible by the use of a high power microscope that is capable of magnifying an image by over 6,000 times or even more. With such a high level of magnification, the embryologist is able to detect minute structural variations in the sperm of a semen sample that would have otherwise not been visible with a normal microscope. After carefully sifting through the sample, the embryologist chooses a morphologically fit sperm for injecting into the egg.
Once the most viable sperm has been identified and isolated, the IMSI fertility treatment follows the exact same procedure as ICSI.
The IMSI procedure enables embryologists to prevent structurally deficient or abnormal sperm from entering an egg and fertilizing it. The procedure is also favorable for men who have a higher than normal amount of abnormal sperm in their semen and who haven’t had success with previous IVF-ICSI attempts. In such cases, an IMSI IVF process acts as an enhanced selection mechanism that can possibly increase the chances of fertilization and normal embryo growth.
As mentioned above, the sperm sample of the male partner is magnified up to 6,000 times, which allows embryologists to identify and exclude sperm that show any kind of structural abnormalities. Compare this to traditional techniques of selecting sperm that have the embryologist observing sperm for abnormalities at just 400 times magnification.
IMSI is recommended under the following conditions,
If IMSI is successful, the resulting embryo can be transferred to the intending mother’s womb. However, in case the mother is not fit enough to sustain a pregnancy, the option of surrogacy at a reputed surrogacy center in India is the way to go.
Since it involves micro-injecting only morphologically best sperm into an egg, the IMSI success rate is believed to be higher than conventional ICSI. However, the success rate also greatly varies on a case by case basis.
The IMSI cost similarly is higher than that of ICSI. However, the increase in cost is only incremental.
Since it involves micro-injecting only morphologically best sperm into an egg, the IMSI success rate is believed to be higher than conventional ICSI. However, the success rate also greatly varies on a case by case basis. The IMSI cost similarly is higher than that of ICSI. However, the increase in cost is only incremental.